New psychology is neuroscience and neurobiology.

We found that the cortex, via cortico-lateral-amygdala somatostatin neurons (CLA-SOM), has a direct inhibitory influence on the output of the LA principal neurons. Our results define a CLA long-range inhibitory circuit (CLA-SOM inhibitory projections → LA principal neurons) underlying the control of spike timing/generation in LA and LA–AC projecting neurons, and attributes a specific function to a genetically defined type of cortical long-range GABAergic neurons in CLA communication.

SIGNIFICANCE STATEMENT It is very well established that cortical auditory inputs to the lateral amygdala are exclusively excitatory and that cortico-amygdala neuronal activity has been shown to be involved in sound-driven aversive/fear behavior. Here, for the first time, we show that the lateral amygdala receives long-range GABAergic projection from the auditory cortex and these form direct monosynaptic inhibitory connections onto lateral amygdala principal neurons. Our results define a cellular basis for direct inhibitory communication from auditory cortex to the lateral amygdala, suggesting that the timing and ratio of excitation and inhibition, two opposing forces in the mammalian cerebral cortex, can dynamically affect the output of the lateral amygdala, providing a general mechanism for fear/aversive behavior driven by auditory stimuli.

View Full Text

https://www.jneurosci.org/content/39/43/8424

Comments

The surprisingly dramatic role of nutrition in mental health | Julia Ruc...

example of gut brain connection. Premature infants

The research team found that the overgrowth of the gastrointestinal tract with the bacterium Klebsiella is associated with an increased presence of certain immune cells and the development of neurological damage in premature babies. The study is now published in the journal Cell Host & Microbe.

Donuts sugar another garbage that you’ll eat anyway but

Featured Articles in Internal Medicine IN THE NEWS The untouchables: 7 foods to avoid at all costs Naveed Saleh, MD, MS, for MDLinx | August 23, 2019 Many people consider themselves food experts. After all, we’ve all been eating food for our whole lives, haven’t we? But there are certain foods that are unhealthy, and it’s not always obvious which ones they are. ADVERTISEMENT Despite the fact that oysters are bivalve filter feeders that munch on ocean sediment, people seem to love eating them raw. To help, MDLinx has compiled a list of foods you should avoid. And while it’s probably unrealistic to think that you’d never eat any of the foods on this list again, for the benefit of your health, it’s probably best to eschew them at all costs. The risks of eating these health culprits are downright scary and can contribute to several different types of disease—both acute (ie, infection) and chronic (ie, heart disease). Processed deli meats

NeuroGuru log kent Norton

Search This Blog